Unlocking the epigenetic barriers to Human tissue regeneration

Abstract

The limited regenerative capability of human tissues often results in structural and functional impairments, affecting quality of life. Recent advances in epigenetics have accelerated research on tissue regeneration. Specifically, epigenetic processes orchestrate regenerative dynamics across molecular and ecological scales. Biochemical and nanotechnological tools bridge fundamental epigenetic research with clinical applications, while emerging technologies and artificial intelligence enhance our understanding of epigenetic regulation in regeneration. Future perspectives are also discussed to explore strategies for unlocking epigenetic barriers and advancing research on human tissue regeneration.